Bicycle Therapeutics presents initial Duravelo-2 data showing comparable ORR and lower toxicity in mUC

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2026.05.21 21:13
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Bicycle Therapeutics reported initial Duravelo-2 data for zelenectide in metastatic urothelial cancer, showing a 65% unconfirmed overall response rate (ORR) and a favorable safety profile. Key findings include a median treatment duration of 6.3 months, with 65% of patients still on treatment. Cohort 2 showed a 37% ORR. Updated Duravelo-1 data indicated a 59% unconfirmed ORR and median progression-free survival of 13.0 months.