XUANZHUBIO-B

Xuanzhu Biopharmaceutical Co., Ltd. engages in the development, industrialization, and commercialization of small-molecule chemical drugs and macromolecular biopharmaceuticals in China. Its lead product candidates include Core- KBP-3571 for the treatment of duodenal ulcer, adult reflux esophagitis, pylori eradication; XZP-3287, a CDK4/6 inhibitor for the treatment of HR+/HER2- advanced breast cancer, R+/HER2- locally advanced or metastatic breast cancer, and adjuvant therapy for HR+/HER2- early breast cancer; and XZP-3621, a first-line treatment for patients with anaplastic lymphoma kinase positive advanced non-small-cell lung cancer, post-operative adjuvant therapy for patients with ALK-positive non-small cell lung cancer. The company also develops KM501, a first-in-class HER2/HER2 bispecific antibody drug conjugate, which is in Phase I clinical trial; KM602, which is in Phase I clinical trial for anti-tumor; XZP-7797, a selective and brain-penetrating poly ADP-ribose polymerase 1 inhibitor; and XZP-6924, a ubiquitin-specific protease 1 (USP1) inhibitor.